Closed-Loop Neural Decoding for High-Degree-of-Freedom Paralysis Neuro-Prosthetics

Restoring natural reach-and-grasp kinematics in tetraplegic patients requires continuous multidimensional motor decoding. Latency delays between intention and prosthetic articulation above 50 milliseconds break the illusion of agency. This paper presents low-latency Kalman filter decoders running on FPGA edge gates.

Continuous Velocity State Estimation

Recursive steady-state Kalman filters update 3D arm position and hand aperture estimates every 10 milliseconds, dynamically adjusting noise covariance matrices to compensate for electrode signal dropout.

Haptic Somatosensory Feedback Injection

Prosthetic fingertips equipped with piezo-resistive pressure sensors transmit tactile data back to cortical sensory arrays via intracortical microstimulation (ICMS), completing the closed biological loop.

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